Outcome | Change in CPAP group Mean (SD) | Change in BVS group Mean (SD) | Mean difference between treatments(95% CI) | p Value† |
Paco2 (mm Hg) | −5.8 (8.4)* | −6.9 (6.7)* | 1.04 (−4.5 to 6.6) | 0.7 |
Awake Spo2 (%) | 6 (3)* | 8 (5)* | 1.9 (−5. 2 to 1.3) | 0.24 |
Bicarbonate (mmol/l) | −2.3 (8.5)* | −2.5 (2.5)* | 0.2 (−4.2 to 4.6) | 0.93 |
Weight loss (kg) | −4.9 (7.8)* | −5.6 (9.4)* | 0.7 (−5.2 to 6.5) | 0.82 |
Mean nightly therapy use (h) | 5.8 (2.4) | 6.1 (2.1) | 0.33 (−1.8 to 1.2) | 0.66 |
ESS | −6 (8)* | −9 (5)** | 2.89 (−1.78 to 7.56) | 0.21 |
PSQI | −1.93 (3.5) | −5.6 (3.9)** | 3.67 (0.82 to 6.5) | 0.013 |
BVS, bilevel ventilatory support; CPAP, continuous positive airway pressure; Paco2, arterial carbon dioxide tension; Spo2, oxygen saturation; ESS, Epworth Sleepiness Scale; PSQI, Pittsburgh Sleep Quality Index.
*p<0.05, **p<0.001, within group changes from baseline.
†p Value denotes mean difference between CPAP and BVS treatment groups using unpaired t tests.