Table 1 Arterial blood gases and respiratory physiology measurements in rats
Baseline2 h4 h
Pao2 (kPa)
    NS13.5 (12.0–15.0)11.3 (9.3–13.3)9.7 (8.0–11.4)*
    IL-1Ra12.9 (12.2–13.6)12.4 (10–14.8)11.6 (9.5–13.7)
Paco2 (kPa)
    NS4.9 (4.2–5.6)5.7 (5.2–6.2)5.3 (3.7–6.9)
    IL-1Ra5.4 (4.2–6.6)5.7 (4.5–6.9)6.1 (4.8–7.4)
pH
    NS7.43 (7.37–7.49)7.39 (7.36–7.42)7.32 (7.24–7.40)
    IL-1Ra7.41 (7.35–7.47)7.42 (7.34–7.48)7.39 (7.33–7.45)
Respiratory system compliance (ml/cm H2O)
    NS0.34 (0.32–0.36)0.28 (0.25–0.31)0.26 (0.22–0.30)*
    IL-1Ra0.33 (0.29–0.37)0.31 (0.28–0.34)0.30 (0.27–0.33)
  • Data are mean (SD).

  • Pao2. Paco2, arterial oxygen and carbon dioxide tensions; NS, normal saline; IL-1Ra, IL-1 receptor antagonist.

  • *p<0.05 vs baseline value in the same group.