Sex | Age (y) | Duration of asthma (y) | FEV1 (l) | FEV1 (% pred) | Total IgE (kU/l) | Specific IgE (kU/l) | Allergen | Dose (AU) | Medication |
F | 24 | 11 | 3.3 | 95 | 226 | 56.6 | D pter | 10 | BA |
F | 22 | 10 | 4.1 | 105 | 545 | 12.6 | Rye | 76 | BA |
M | 34 | 24 | 5.7 | 124 | 127 | 35.2 | Birch | 23 | BA, IC |
F* | 24 | 2 | 4.0 | 105 | 64 | 13.8 | D pter | 2 | BA, CR, OAH |
F | 26 | 10 | 3.6 | 101 | 121 | 34.5 | Birch | 28 | BA, OAH |
F | 25 | 2 | 3.9 | 123 | 20 | 5.3 | Birch | 14 | BA, IC |
M | 37 | 10 | 4.9 | 104 | 490 | >100.0 | Birch | 135 | OAH |
M | 22 | 1 | 4.6 | 102 | 695 | >100.0 | Rye | 60 | None |
F | 20 | 14 | 3.9 | 112 | 2047 | 27.5 | Birch | 53 | BA, IC |
M | 23 | 5 | 3.6 | 77 | 548 | 26.1 | Birch | 76 | BA |
F | 23 | 15 | 3.5 | 92 | 564 | 77.1 | D pter | 25 | BA |
F | 25 | 17 | 3.2 | 94 | 96 | 4.0 | Birch | 30 | BA, IC |
F* | 25 | 3 | 4.0 | 105 | 64 | 16.9 | D pter | 2 | BA, CR |
F | 24 | 21 | 3.5 | 102 | 155 | 5.2 | Rye | 4 | BA, CR |
M | 20 | 13 | 4.8 | 114 | 141 | 18.7 | Rye | 1150 | BA, CR |
F | 23 | 3 | 3.8 | 99 | 83 | 20.9 | Rye | 1430 | BA, IC |
F | 28 | 10 | 2.8 | 105 | 22 | 6.9 | Birch | 64 | BA, CR, IC |
M | 34 | 10 | 4.6 | 114 | 172 | 30.7 | Rye | 46 | BA |
M | 24 | 17 | 4.6 | 94 | 368 | 66.3 | D pter | 49 | BA, CR, OAH |
M | 24 | 4 | 4.8 | 105 | 104 | 8.3 | D pter | 71 | BA |
F | 22 | 2 | 3.3 | 110 | 134 | 39.6 | Rye | 340 | IC |
M | 24 | 16 | 4.5 | 97 | 1335 | >100.0 | Birch | 123 | BA |
M | 23 | 4 | 4.8 | 107 | 622 | 46.8 | D pter | 2180 | BA, IC |
Sex, age and duration of asthma of the patients, prebronchodilator FEV1, medication prior to the study (BA, CR, IC, OAH), serum levels of total (normal range <100 kU/l) and allergen specific (normal range <0.7 kU/l) IgE and the allergen and dose used for segmental allergen challenge.
*One patient participated once in the 24 h protocol and once in the 72 h protocol with 15 months in between.
AU, allergen units; BA, inhaled β2 agonist; CR, cromoglycate; D pter, Dermatophagoides pteronyssinus; FEV1, forced expiratory volume in 1 s; IC, inhaled corticosteroid; IgE, immunoglobulin E; OAH, oral antihistamine.