Table 2 Median intra-patient coefficient of variation (CV) for each mediator

Mediator	CV (%)	IQR
IL-1β (pM)	19.4	11–33
TNFα (pM)	30.3	13–88
LTB4 (nM)	39.9	22–165
CXCL8 (nM)	30.8	19–63
GROα (nM)	16.2	10–29
Absolute neutrophil count (106/ml)	77.3	42–180
Absolute macrophage count (106/ml)	74.2	41–102
MPO (mg/ml)	79.3	53–138

The median intra-patient CV is derived from each individual patient’s CV. Each patient’s mediator-specific CV was calculated using data from 11 sequential visits.
IL-1β, interleukin 1β; TNFα, tumour necrosis factor α; LTB4, leucotriene B4; CXCL8, interleukin 8; GROα, growth-related oncogene α; MPO, myeloperoxidase; IQR, interquartile range.