Table 4 Patient recorded diary card assessments and Transitional Dyspnoea Index scores

Parameter	Baseline	Treatment value at day 14			Treatment differences (97.5% CI); p value
Parameter	Baseline	SFC+TIO	TIO	SFC	Triple vs TIO	Triple vs SFC
Mean (SD) TDI total score	6.3 (1.73)	2.3 (2.55)	0.2 (3.09)	1.7 (2.76)	2.2 (0.8, 3.5); p<0.001	0.7 (−0.7, 2.1); p = 0.238
Improvement: TDI⩾1 (n (%))		21 (72)	8 (27)	14 (54)
No change: TDI = 0		6 (21)	15 (50)	9 (35)
Deterioration: TDI⩽−1		2 (7)	7 (23)	3 (12)
Mean (SD) occasions of rescue medication use over 24 h	3.2 (2.64)	1.6 (1.60)	2.6 (2.50)	2.0 (2.23)	−1.0 (−1.5, −0.6); p<0.001	−0.6 (−1.1, −0.1); p = 0.013
					Treatment differences (SE); p value
Mean (SD) morning PEF (treatment period)	221.4 (84.8)	265.8 (99.2)	244.2 (101.2)	249.1 (91.0)	14.9 (−0.4, 30.3); p = 0.029	11.0 (−5.1, 27.1); p = 0.121

PEF, peak expiratory flow; SFC, salmeterol/fluticasone propionate combination; TDI, Transitional Dyspnoea Index; TIO, tiotropium.