Table 3 Correlation between LCI, FEV1, FEF75 (standard deviation scores) and structural abnormalities
HRCT scoreBronchiectasisMucus plugsAirway wall thicknessParenchymaAir trapping
LCI0.85***0.64***0.73***0.76***0.79***0.65***
FEV1−0.62***−0.35*−0.45**−0.55***−0.58***−0.59***
FEF75−0.66***−0.44**−0.49***−0.56***−0.65***−0.57***

  • LCI, lung clearance index; FEV1, forced expiratory volume in 1 s; FEF75, maximal expiratory flow when 75% of forced vital capacity was expired; HRCT, high-resolution CT.

  • Data shown as Spearman rank correlation coefficients (Rs).

  • *p<0.05; **p<0.01; ***p<0.001.