Table 2 Comparison of characteristics of groups of children defined by V′maxFRC at 1 month of age (dichotomised about the median value into high or low) and percentage change in V′maxFRC between 1 and 12 months of age (dichotomised about the median value into high and low)
Low V′maxFRC at 1 month and low V′max growth(n = 21)High V′maxFRC at 1 month and low V′max growth(n = 56)Low V′maxFRC at 1 month and high V′max growth(n = 56)High V′maxFRC at 1 month and high V′max growth(n = 22)Trend test
Diagnosed asthma by 3 years of age38% (8/21)29% (15/52)32% (14/52)13% (3/24)p = 0.017*
Diagnosed asthma at 4–6 years of age33% (6/18)20% (10/50)33% (16/49)11% (2/19)p = 0.149*
Diagnosed asthma at 11 years20% (4/20)13% (6/46)16% (7/45)5% (1/20)p = 0.456*
Mean (SD) % change in weight between 1 and 12 months230 (28)222 (32)206 (29)210 (24)p = 0.003
Mean (SD) birth weight (kg)3.2 (0.5)3.6 (0.4)3.5 (0.5)3.4 (0.5)p = 0.039
Exclusive breast feeding for at least 6 months24% (4/17)37% (18/49)44% (18/41)31% (5/16)p = 0.495
Male (number)67% (14)54% (30)63% (35)41% (9)p = 0.253
Maternal smoking during pregnancy19% (4/21)13% (7/56)23% (13/56)23% (5/22)p = 0.493
Parental asthma35% (7/20)35% (19/55)33% (18/55)23% (5/22)p = 0.772
  • V′maxFRC, maximal flow at functional residual capacity.

  • *Adjusted for percentage weight gain between 1 and 12 months.