Table 2 Mean (SD) changes in arterial blood gases after 3 months of treatment
BaselineAfter 3 monthsChange within groupBetween group difference in change (95% CI)
Paco2 (kPa)
    N+R6.89 (0.68)6.44 (0.69)−0.45−0.32 (−0.6 to −0.1)*
    R6.81 (0.81)6.71 (0.58)−0.10
Pao2 (kPa)
    N+R7.82 (1.03)8.26 (1.20)0.440.25 (−0.2 to 0.7)
    R8.33 (1.25)8.33 (0.93)0.01
HCO3 (mmol/l)
    N+R29.2 (2.3)28.4 (2.4)−0.9−0.7 (−1.8 to 0.4)
    R29.4 (2.7)29.1 (1.8)−0.3
  • HCO3, bicarbonate; N+R, non-invasive positive pressure ventilation (NIPPV) + rehabilitation group; Paco2, arterial carbon dioxide pressure; Pao2, arterial oxygen pressure; R, rehabilitation group.

  • All assessments at daytime on room air at rest without NIPPV.

  • *Significant difference in change between groups.