Table 1 Clinical characteristics of study patients
AIA (n = 19)ATA (n = 21)p value
Age (years)42.4 (13.3)43.6 (12.5)0.613 (NS)
41 (31–53)43 (36–53)
Sex (F/M)11/813/80.967 (NS)
Duration of asthma (years)7.8 (7.5)10.6 (9.4)0.328 (NS)
5 (1–11)7 (3–18)
Inhaled steroids (yes/no)11/817/40.170 (NS)
Inhaled steroids (μg/day)1690 (712)1424 (821)0.204 (NS)
1600 (1000–2000)1000 (800–1600)
FEV1 baseline (% predicted) placebo day90.4 (10.7)90.5 (12.1)0.683 (NS)
94.8 (82.5–98.1)91.4 (81.5–93.6)
FEV1 baseline (% predicted) aspirin day91.6 (10.8)94.1 (12.0)0.708 (NS)
93.0 (87.7–98.4)94.0 (81.9–100.2)
FEV1 baseline (% predicted) celecoxib day92.4 (12.4)90.0 (13.8)0.631 (NS)
90.9 (85.7–98.6)86.6 (78.0–95.7)
Total IgE (IU/ml)182.3 (229.8)206.0 (241.6)0.844 (NS)
121 (45.4–226)91.9 (39.9–345)
Skin prick test (n) positive/negative8/79/90.849 (NS)
Blood eosinophil count425.4 (328.4)356.7 (246.7)0.667 (NS)
371 (159–669)296 (1164–502)
  • Values are expressed as mean (SD) or median (25–75% percentiles).

  • AIA, aspirin-induced asthma; ATA, aspirin-tolerant asthma; FEV1, forced expiratory volume in 1 s; NS, not significant.