| COPD | Controls | ||
| Age (years) and sex | 64 (8) 13M 6F | 66 (7) 5M 7F | |
| FEV1 (% predicted) | 37 (20)*** | 107 (8) | |
| RV/TLC (%) | 58 (13)*** | 36 (5) | |
| TLCO (% predicted) | 40 (15)*** | 89 (11) | |
| PaO2 (kPa) | 9.4 (1.4)** | 11.2 (0.9) | |
| Fat-free mass index (FFMI, kg/m2) | 15.9 (2)* | 17.6 (2.6) | |
| MTCSA (cm2) | 104 (27) | 116 (26) | |
| MURF-1/β2M | 0.136 (0.081) | 0.135 (0.082) | |
| MURF-1/RPLPO | 0.045(0.014) | 0.056 (0.018) | |
| Atrogin-1/β2M | 0.439 (0.376) | 0.727 (0.319) | |
| Atrogin-1/RPLPO | 0.211 (0.1)* | 0.056 (0.018) |
Mean (SD) values (median and median absolute deviation).
***p = 0.0001; **p = 0.0004; * p<0.05; indicating significant group differences.