Abstract P204
COPDControls
Age (years) and sex64 (8) 13M 6F66 (7) 5M 7F
FEV1 (% predicted)37 (20)***107 (8)
RV/TLC (%)58 (13)***36 (5)
TLCO (% predicted)40 (15)***89 (11)
PaO2 (kPa)9.4 (1.4)**11.2 (0.9)
Fat-free mass index (FFMI, kg/m2)15.9 (2)*17.6 (2.6)
MTCSA (cm2)104 (27)116 (26)
MURF-1/β2M0.136 (0.081)0.135 (0.082)
MURF-1/RPLPO0.045(0.014)0.056 (0.018)
Atrogin-1/β2M0.439 (0.376)0.727 (0.319)
Atrogin-1/RPLPO0.211 (0.1)*0.056 (0.018)
  • Mean (SD) values (median and median absolute deviation).

  • ***p = 0.0001; **p = 0.0004; * p<0.05; indicating significant group differences.