Empirical antibiotic treatment regimens for adults with pneumonic and non-pneumonic lower respiratory tract infections (including exacerbations of COPD and acute bronchitis) complicating influenza managed in the community
| Preferred | Alternative* |
|---|---|
| *An alternative regimen is provided for those intolerant of or hypersensitive to preferred regimen. | |
| †Clarithromycin may be substituted for those with gastrointestinal intolerance to oral erythromycin and also has the benefit of twice daily dosage and better cover against H influenzae. | |
| od, once daily; bd, twice; tds, 3 times; qds, 4 times. | |
| Doxycycline 200 mg stat and 100 mg od PO or co-amoxiclav 625 mg tds PO (for 1 week) | Macrolide (erythromycin 500 mg qds PO or clarithromycin 500 mg bd† PO) |