Table 2 Association between risk for current asthma and adiposity with and without adjustment for serum adiponectin concentration
Models for adiposity measureWomenMen
No with current asthma/totalOR (95% CI)No with current asthma/totalOR (95% CI)
Underweight and normal weight31/585118/3561
Overweight37/4201.68 (1.01 to 2.79)39/5591.54 (0.84 to 2.80)
Obese100/5983.31 (2.00 to 5.46)21/3721.33 (0.61 to 2.89)
p Value for Wald χ2<0.0010.37
BMI adjusted for adiponectin
Underweight and normal weight31/585118/3561
Overweight37/4201.63 (0.98 to 2.74)39/5591.64 (0.89 to 3.02)
Obese100/5983.19 (1.91 to 5.32)21/3721.45 (0.66 to 3.17)
p Value for Wald χ2<0.0010.28
  • Covariates adjusted in each logistic regression model include age, race, smoking status, ln(physical activity), history of diabetes and ln(insulin resistance). In addition, when indicated, group-specific tertiles of serum adiponectin concentration were also adjusted.

  • The interaction between sex and BMI on current asthma was significant (p = 0.004 in both models).

  • Adiponectin tertile cut-off points are 1.2–9.0, 9.0–14.4 and 14.4–94.8 mg/l for women and 1.0–6.0, 6.0–9.6 and 9.6–64.0 mg/l for men.

  • Similar results were obtained when the underweight and normal weight categories were analysed separately with the latter serving as the referent category.

  • BMI categories are defined as follows: underweight <18.5 kg/m2; normal weight 18.5–24.9 kg/m2; overweight 25.0–29.9 kg/m2; obese ⩾30 kg/m2.

  • BMI, body mass index; CI, confidence interval; OR, odds ratio.