Table 2

 Baseline haemodynamics and spirometric parameters of the IPAH, distal CTEPH and proximal CTEPH groups

IPAH(n = 96)Distal CTEPH(n = 35)Proximal CTEPH(n = 68)p Value (ANOVA)
Values are mean (SD).
CTEPH, chronic thromboembolic pulmonary hypertension; FEV1, forced expiratory volume in1 s; FVC, forced vital capacity; IPAH, idiopathic pulmonary arterial hypertension; Kco, carbon monoxide transfer coefficient; mPAP, mean pulmonary artery pressure; RAP, resting arterial pressure; TLC, total lung capacity; Tlco, carbon monoxide transfer factor; TPR, total pulmonary resistance.
Significant pairwise comparisons are listed below:
*p = 0.02 (IPAH vs proximal CTEPH).
†p<0.001 (IPAH vs proximal CTEPH); p = 0.008 (IPAH vs distal CTEPH).
‡p<0.001 (IPAH vs proximal CTEPH); p = 0.001 (IPAH vs distal CTEPH).
§p = 0.007 (distal CTEPH vs proximal CTEPH).
¶p = 0.01 (IPAH vs proximal CTEPH); p = 0.006 (proximal CTEPH vs distal CTEPH).
**p = 0.002 (IPAH vs proximal CTEPH).
Haemodynamics
    RAP9.5 (6)10.2 (7.9)8.6 (5.8)0.45
    Cardiac index1.91 (0.68)2.11 (0.68)2.07 (0.67)0.23
    mPAP†54.8 (13.1)47.3 (11.9)45.4 (12.0)<0.001
    TPR‡18.1 (8.3)12.9 (5.2)12.4 (5.2)<0.001
Pulmonary function
    FEV1 (% predicted)84.0 (16)74.7 (22.1)80.4 (18.5)0.07
    FVC (% predicted)§92.0 (16.8)83.3 (24.7)95.7 (16.9)0.009
    TLC (% predicted)98.2 (15.2)90.8 (19.8)95.6 (15.5)0.09
    Tlco (% predicted)¶66.3 (19.3)62.8 (13.4)75.5 (17.7)0.002
    Kco (% predicted)**78.8 (22.1)85.3 (17.4)91.6 (19.3)0.002