| Survivors (n = 88) Mean (SD) | Non-survivors (n = 61) Mean (SD) | Mean difference/ OR (95% CI) | p Value between groups | |
| Age (years) | 44.2 (16.7) | 55.1 (17.0) | 10.6 (5.2 to 16.1) | <0.001 |
| Trauma | 11 (12%)* | 2 (3%)* | 0.3 (0.1 to 1.3) | <0.05 |
| Gender (% female) | 24 (27%)* | 25 (41%)* | 1.8 (0.9 to 3.7) | <0.1 |
| OI (cm H2O/kPa) | 73.5 (42.0) | 111.8 (70.5) | 33.8 (15 to 52.5) | <0.001 |
| Pao2/Fio2 (kPa) | 20.7 (8.3) | 16.4 (8.3) | −2.5 (−5.8 to −0.7) | 0.003 |
| Fio2 | 0.7 (0.2) | 0.8 (0.2) | 0.04 (−0.03 to 0.1) | 0.01 |
| Pao2 (kPa)† | 10.9 (4.4) | 9.6 (2.9) | 1.2 (3.2 to 0.8) | 0.05 |
| Vt (ml/kg PBW) | 7.9 (1.9) | 7.2 (2.3) | −0.5 (−1.2 to 0.2) | 0.06 |
| f Value | 21.6 (7.6) | 24.1 (8.5) | 1.9 (−0.8 to 4.7) | 0.07 |
| Pplat (cm H2O) | 25.5 (6.0) | 27.6 (7.6) | 2.1 (−0.1 to 4.6) | 0.09 |
| Mean Paw (cm H2O) | 14.0 (4.0) | 15.3 (5.5) | 0.9 (−.9 to 2.6) | 0.1 |
| Crs (ml/cm H2O) | 29.2 (9.7) | 26.7 (11.2) | −2.0 (−5.4 to 1.5) | 0.2 |
| PEEP | 7.3 (2.8) | 7.9 (3.3) | 0.6 (−0.5 to 1.6) | 0.3 |
| SAPS II | 39.2 (13.7) | 50.6 (12.4) | 10.5 (5.8 to 15.3) | <0.001 |
| APACHE II | 17.4 (7.1) | 22.5 (7.0) | 4.6 (2.1 to 7.2) | <0.001 |
| pH | 7.37 (0.1) | 7.30 (0.1) | −0.06 (−0.1 to − 0.02) | 0.001 |
| Base deficit–day 1 | −2.15 (5.78) | −4.97 (6.70) | −1.5 (−4.0 to 0.9) | 0.008 |
| Cirrhosis (n (%)) | 7 (8)* | 14 (25)* | 3.7 (1.4 to 9.2) | 0.005 |
*Percentages of row total.
†Value at time of diagnosis of lung injury. In column 4, continuous values are displayed as mean differences and categorical values are displayed as ORs.
APACHE, Acute Physiology and Chronic Health Evaluation; Crs, respiratory system compliance; f, respiratory frequency; Fio2, inspired oxygen fraction; OI, oxygenation index; Pao2, arterial oxygen partial pressure; PBW, predicted body weight; PEEP, positive end expiratory pressure; mean Paw, mean airway pressure; Pplat, end inspiratory plateau pressure; SAPS II, Severe Acute Physiology Score II; Vt, tidal volume.