Table 2 Associations of wheezing phenotype with asthma and atopy in 5397 children with complete data on wheezing and asthma at 7.5 years and 4331 children with skin prick test data at 7–8 years
PhenotypePhysician-diagnosed asthmaAtopy (any skin prick sensitivity)Skin prick sensitivity to D pteronyssinus*Skin prick sensitivity to cat*Skin prick sensitivity to grass*
n/total (%)OR (95% CI)n/total (%)OR (95% CI)n/total (%)OR (95% CI)n/total (%)OR (95% CI)n/total (%)OR (95% CI)
Transient early79/931 (8.5%)2.46 (1.48 to 4.09)95/700 (13.6%)0.8 (0.55 to 1.17)52/707 (7.4%)0.84 (0.51 to 1.38)22/702 (3.1%)0.86 (0.42 to 1.77)52/706 (7.4%)0.80 (0.48 to 1.32)
Prolonged early183/509 (36.0%)14.87 (10.68 to 20.71)57/383 (14.9%)0.89 (0.58 to 1.38)32/387 (8.3%)0.99 (0.56 to 1.72)11/384 (2.9%)0.77 (0.27 to 2.2)25/386 (6.5%)0.69 (0.36 to 1.35)
Intermediate141/152 (92.8%)325.75 (137.78 to 770.14)71/114 (62.3%)8.36 (5.24 to 13.36)59/116 (50.9%)11.12 (7.06 to 17.53)42/115 (36.5%)15.51 (9.45 to 25.46)37/115 (32.2%)4.83 (2.98 to 7.82)
Late260/341 (76.2%)84.60 (56.00 to 127.8)145/257 (56.4%)6.62 (4.67 to 9.39)93/259 (35.9%)5.97 (4.13 to 8.63)69/257 (26.8%)9.73 (6.32 to 14.98)101/259 (39.0%)6.54 (4.57 to 9.35)
Persistent362/393 (92.1%)307.93 (185.86 to 510.18)123/296 (41.6%)3.64 (2.76 to 4.81)91/299 (30.4%)4.66 (3.42 to 6.36)66/296 (22.3%)7.54 (5.17 to 11)73/298 (24.5%)3.27 (2.37 to 4.53)
Never/infrequent126/3397 (3.7%1 (reference)419/2554 (16.4%)1 (reference)219/2580 (8.5%)1 (reference)92/2560 (3.6%)1 (reference)232/2575 (9.0%)1 (reference)
  • *Mean weal diameter ⩾2 mm. CI, confidence interval; OR, odds ratio.