Table 2

Dosing regimen, recorded levels & previous exposure to aminoglycosides

No.	Aminoglycoside	Dose/kg	Times/day	Duration of IV aminoglycoside*	Maximum trough aminoglycoside level	Previous aminoglycosides	No. previous courses of IV antibiotics†	Interval since last IV aminoglycoside (months)
IV, intravenous; NR, not recorded.
*Not always possible to determine from the case notes whether a course of treatment included an aminoglycoside.
1	Gentamicin	2.91	3	15	1.6	No	0
2	Gentamicin	5.06	3	27	11.0	Yes	35	3
3	Gentamicin + tobramycin	3.92	3	10	9.8	Yes	1	8
4	Gentamicin	4.29	3	11	1.0	Yes	1	30
5	Gentamicin	2.52	3	9	5.9	No	0
6	Tobramycin	4.08	2	3	0.2	Yes	13	2
7	Gentamicin	4.19	3	17	0.7	Yes	8	1
8	None					Yes	25	6
9	Gentamicin	NR	NR		13	Yes	22	11
10	Tobramycin	3.25	3	15	0.9	Yes	25	2
11	Gentamicin	2.58	1	13	<1	Yes	72	4
12	Gentamicin	3.33	3	11	1.8	Yes	15	4
13	Gentamicin	5.16	3	14	1.3	No	0
14	Gentamicin	4.16	3	15	2.1	No	0
15	Tobramycin	4.49	3	49	2.9	Yes	25	3
16	Tobramycin	10.00	1	34	0.2	Yes	14	7
17	Tobramycin	4.12	3	6	5.6	Yes	15	2
18	Gentamicin	3.29	3	7	<1	Yes	35	12
19	Gentamicin	3.98	3	11	<1	Yes	6	7
20	None					Yes	5	4
21	None					Yes	15	2
22	Gentamicin	3.70	3	10	6.7	Yes	2	8
23	Gentamicin	3.33	3	9	4.5	Yes	2	8
24	Gentamicin	3.28	3	19	2.1	Yes	2	59