Table 1

 Baseline demographic and physiological data

VariableARDS group
Standard care(n = 17)Surfactant treatment(n = 14)
Data are presented as median (25–75th percentile).
ARS, acute respiratory respiratory syndrome; APACHE, Acute Physiology and Chronic Health Evaluation; PEEP, positive end-expiratory pressure; Pao2/Fio2, arterial oxygen tension/fractional inspired oxygen.
Pao2/Fio2 and PEEP values represent the mean of three readings over the 6 h baseline period.
Age (years)50.5 (43.8–64.0)50.0 (36.0–58.2)
Sex (M/F)12/511/3
Ethnic origin, n (%)
    Caucasian16 (94.1)12 (85.7)
    African1 (5.9)1 (7.1)
    Asian0 (0)1 (7.1)
Predisposing events,n (%)
    Trauma/surgery7 (41.2)7 (50)
    Sepsis syndrome7 (41.2)6 (42.9)
    Pneumonia5 (29.4)6 (42.9)
    Pancreatitis2 (11.8)1 (7.1)
    Gastric aspiration2 (11.8)1 (7.1)
    Polytransfusion1 (5.9)0 (0)
    Burn1 (5.9)0 (0)
    Others1 (5.9)0 (0)
Hours from diagnosis to initial treatment38.0 (21.0–74.0)23.2 (9.0–53.5)
Modified APACHE II score15.0 (10.8–21.2)13.0 (10.2–15.8)
PEEP (cm H2O)12 (12–14)12 (12–12)
Pao2/Fio2122.5 (96.5–147.8)126.8 (111.8–152.2)