Table 3 Associations between exacerbations and GORD symptoms in patients with COPD
GORD symptomsCOPD exacerbationExacerbation frequency over 6 months
Did not occurDid occur
Negative36240.70 (1.20
Positive5171.73 (1.58
p Value<0.01<0.01
  • Data were evaluated by the χ2 test and the unpaired t test. The relative risk for the occurrence of exacerbation in patients with GORD symptoms compared with patients without such symptoms was 1.93 (95% CI 1.32 to 2.84; p<0.01).

  • COPD, chronic obstructive pulmonary disease; GORD, gastro-oesophageal reflux disease.