Genotypes | Genotype frequency (%) | OR* (95% CI) | p Value* |
---|---|---|---|
*Estimated by logistic regression models, adjusting for age, sex, history of alcohol abuse, diabetes, steroid use, APACHE III score and multiple (>1) risk factors for ARDS. | |||
†The genotypes were coded as continuous variables (1, 2 and 3 for wild type, heterozygous and homozygous genotypes, respectively) and entered together into the logistic regression model. | |||
460TT | 29.4 | 1.00 | |
460CT | 46.7 | 1.33 (0.83 to 2.14) | 0.24 |
460CC | 23.9 | 0.77 (0.44 to 1.35) | 0.37 |
405GG | 43.9 | 1.00 | |
405CG | 43.4 | 1.37 (0.84 to 2.24) | 0.20 |
405CC | 12.7 | 0.87 (0.43 to 1.74) | 0.69 |
936CC | 73.9 | 1.00 | |
936CT | 22.8 | 1.60 (0.90 to 2.80) | 0.10 |
936TT | 3.3 | 4.29 (1.12 to 16.40) | 0.03 |
936CT+TT | 26.1 | 1.98 (1.14 to 3.42) | 0.01 |
ptrend† | 1.93 (1.10–1.94) | 0.005 |