Correlation between mesothelin staining and mesothelin level in patients with mesothelioma
| Group | Patient number | Histology | Effusion mesothelin concentration (nM) | Mesothelin staining* | Staining intensity† |
|---|---|---|---|---|---|
| E, equivocal. | |||||
| *A positive result was defined as the presence of membranous stain in more than 20% of tumour cells. | |||||
| †Staining intensity was graded semi-quantitatively as negative, weak (1+), moderate (2+) or strong (3+). | |||||
| <26 nM | 1 | Mixed | 2 | – | |
| 2 | Cytology only | 12 | + | + | |
| 3 | Cytology only | 17 | – | ||
| 4 | Cytology only | 21 | + | + | |
| 5 | Mixed | 22 | – | ||
| 6 | Cytology only | 23 | – | ||
| 7 | Cytology only | 25 | – | ||
| >26 nM | 1 | Cytology only | 42 | + | + |
| 2 | Cytology only | 52 | + | +++ | |
| 3 | Epithelial | 83 | + | ++ | |
| 4 | Epithelial | 110 | + | +++ | |
| 5 | Cytology only | 127 | E | ||
| 6 | Cytology only | 198 | + | +++ | |