Patient characteristics and mesothelin values
| No of cases(M/F) | Median age,years (range) | Mean (SE)mesothelin (nM) | |
|---|---|---|---|
| Pleural effusions | |||
| Mesothelioma | |||
| Epithelial | 12/3 | 66.5 (44–94) | 46.9 (1.1) |
| Biphasic | 4/1 | 68 (48–88) | 30.1 (0.8) |
| Sarcomatoid | 9/0 | 77 (57–82) | 4.5 (1.4) |
| Cytology only | 21/2 | 68.5 (44–89) | 39.2 (1.0) |
| All | 52 | 68.5 (44–94) | 27.7 (1.3) |
| Non-malignant effusions | |||
| Transudate | 22/13 | 75 (48–93) | 4 (0.7) |
| Exudate (non-infection) | 24/6 | 75 (34–94) | 4.3 (0.9) |
| Exudate (infection) | 13/6 | 72 (34–91) | 4.3 (0.9) |
| All | 84 | 75 (12–94) | 4.1 (0.8) |
| Non-mesothelioma malignant effusions | |||
| Lung cancer | 22 | 71 (51–79) | 9.4 (1.1) |
| Non-small cell | 15/4 | 70.5 (51–79) | 10.4 (1.1) |
| Adenocarcinoma | 14/3 | 65 (51–79) | 11.8 (1.1) |
| Squamous cell | 1/0 | 76 | 5.5 |
| Large cell | 0/1 | 71 | 1.8 |
| Small cell | 3/0 | 76.5 (74–79) | 4.8 (0.6) |
| Other cancer | 34 | 66 (33–93) | 4.8 (1.1) |
| Colorectal | 2/3 | 75 (50–88) | 5 (0.6) |
| Hodgkin’s lymphoma | 0/1 | 33 | 9.7 |
| Non-Hodgkin’s lymphoma | 2/4 | 67.5 (52–93) | 5.4 (1.4) |
| Breast | 0/10 | 63 (47–74) | 4.0 (0.6) |
| Gastric | 1/0 | 67 | 4.1 |
| Melanoma | 1/1 | 69 (49–81) | 1.1 (1.1) |
| Pancreatic | 2/0 | 74.5 (74–75) | 24.3 (2.7) |
| Hepatocellular | 1/0 | 46 | 3.8 |
| Sarcoma | 1/0 | 82 | 4.3 |
| Adenoid cystic | 1/0 | 48 | 4.9 |
| Waldenstrom’s | 0/1 | 70 | 7.4 |
| Unknown primary | 2/1 | 72 (70–74) | 7.4 (1.0) |
| All | 56 | 66 (33–93) | 6.3 (1.2) |
| Peritoneal effusions and fluid | |||
| Mesothelioma | |||
| Epithelial | 1/1 | 67 (64–70) | 27.9 (0.9) |
| Cytology only | 5/0 | 68 (45–75) | 59.7 (0.8) |
| All | 1/6 | 68 (45–75) | 48.0 (0.9) |
| Non-mesothelioma malignant effusions | |||
| Ovarian cancer | 0/4 | 65.5 (54–70) | 73.7 (0.8) |
| Other cancer | 7/3 | 62.5 (48–76) | 3.6 (0.7) |
| Breast caner | 0/3 | 66 (48–76) | 5.0 (0.6) |
| Colon cancer | 5/0 | 57 (56–74) | 4.4 (0.2) |
| Lung cancer | 1/0 | 69 | 2.9 |
| Non-Hodgkin’s lymphoma | 1/0 | 59 | 0.6 |
| Non-malignant effusions | |||
| Liver disease | 2/4 | 57 (32–73) | 3.0 (0.6) |
| Dialysis fluid | |||
| End-stage renal failure | 9/6 | 64.5 (36–85) | 0.2 (1.1) |