Univariable and multivariable models for predicting severe airflow obstruction in the 237 PI ZZ non-index men and women
| Men OR (95% CI) | Women OR (95% CI) | |
|---|---|---|
| *Univariate model includes sex (male = 1), pack-years of cigarettes, ever-smoking (yes = 1), asthma (yes = 1), pneumonia (yes = 1), chronic bronchitis (yes = 1), index case (yes = 1). | ||
| †Multivariate model includes sex (male = 1), pack-years of cigarettes, ever-smoking (yes = 1), asthma (yes = 1), pneumonia (yes = 1), chronic bronchitis (yes = 1), index case (yes = 1). | ||
| ‡Estimate for pack-years is for each pack-year smoked. | ||
| Number with severe airflow obstruction | 48/106 | 20/131 |
| Univariable predictors* | ||
| Pack-years of cigarettes‡ | 1.07 (1.04 to 1.11) | 1.07 (1.02 to 1.11) |
| Ever smoking status | 6.14 (2.51 to 15.00) | 7.72 (2.14 to 27.86) |
| History of asthma | 6.70 (2.54 to 17.72) | 2.89(1.10 to 7.62) |
| History of chronic bronchitis | 5.20 (1.96 to 13.82) | 3.20 (1.11 to 9.23) |
| History of pneumonia | 4.61 (2.02 to 10.53) | 2.95 (1.00 to 8.66) |
| Multivariable predictors† | ||
| Pack-years of cigarettes‡ | 1.05 (1.00 to 1.10) | 1.03 (0.98 to 1.08) |
| Ever smoking status | 2.64 (0.65 to 10.68) | 5.41 (1.20 to 24.41) |
| History of asthma | 4.24 (1.38 to 13.07) | 2.44 (0.81 to 7.33) |
| History of chronic bronchitis | 3.76 (1.18 to 11.97) | 1.95 (0.56 to 6.84) |
| History of pneumonia | 4.14 (1.49 to 11.54) | 3.51 (1.04 to 11.85) |