Table 3

 Adjusted* regression of respiratory function (assessed at age 31 years) with birth weight and weight gain† during the first year in men and women in the 1966 Northern Finland Birth Cohort study

Regression modelsMen (n = 2262)Women (n = 2295)
FEV1 (ml)FVC (ml)FEV1 (ml)FVC (ml)
β (95% CI)β (95% CI)β (95% CI)β (95% CI)
Analysis restricted to participants with data on weight gain during the first year.
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.
*Adjusted for gestational age at birth, maternal smoking during pregnancy as well as factors at 31 years: adult height, weight, cigarette smoking (never, former and current) and physical activity level (high versus low).
†Weight during first year minus birth weight.
‡Birth weight and weight gain during the first year included as explanatory variables either separately (models 1 and 2) or together (model 3) in the regression model.
Model 1:
    Birth weight (per 500 g)60.5 (35.1 to 85.9)64.4 (35.2 to 93.6)54.1 (34.4 to 73.8)47.3 (24.8 to 70.0)
Model 2:
    Weight gain during first year† (per 1 kg)12.3 (–10.1 to 34.6)41.8 (16.1 to 67.4)12.0 (–4.3 to 28.4)23.5 (4.9 to 42.0)
Model 3:
    Birth weight (per 500 g)63.7 (38.1 to 89.3)72.4 (43.0 to 101.8)57.5 (37.6 to 77.4)52.6 (29.9 to 75.3)
    Weight gain during first year† (per 1 kg)20.1 (–2.4 to 42.5)50.6 (24.8 to 76.4)19.0 (2.6 to 35.4)29.8 (11.1 to 48.5)