Table 2

 Assessment of prognostic factors using Cox proportional hazard models

VariableUnivariate analysisMultivariate analysis
HR (95% CI)p ValueHR (95% CI)p Value
BMI, body mass index; DLCO, diffusing capacity of lungs for carbon monoxide; FEV1, forced expiratory volume in 1 s; FFMI, Fat-Free Mass Index; QMVC, quadriceps maximal voluntary contraction.
DLCO was not included in the multivariate analysis as data on 23 patients were missing.
Men1.3 (0.64.to 2.62)0.471.61 (0.71 to 3.64)0.25
Age (per 10 years)1.68 (1.19 to 2.36)0.0031.72 (1.14 to 2.6)0.01
BMI (kg/m2)0.96 (0.9 to 1.03)0.30.91 (0.8 to 1.05)0.21
FFMI (kg/m2)0.96 (0.82 to 1.11)0.581.08 (0.81 to 1.45)0.6
FEV1 (% predicted)0.99 (0.97 to 1.01)0.170.98 (0.96 to 1.01)0.13
DLCO (%)0.97 (0.95 to 0.99)0.016
QMVC (10% of BMI)0.92 (0.85 to 0.99)0.0220.91 (0.83 to 0.99)0.036
Currently smoking1.79 (0.82 to 3.93)0.142.06 (0.85 to 5)0.11
Pulmonary rehabilitation0.95 (0.5 to 1.8)0.881.57 (0.75 to 3.3)0.23