Assessment of prognostic factors using Cox proportional hazard models
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p Value | HR (95% CI) | p Value | |
| BMI, body mass index; DLCO, diffusing capacity of lungs for carbon monoxide; FEV1, forced expiratory volume in 1 s; FFMI, Fat-Free Mass Index; QMVC, quadriceps maximal voluntary contraction. | ||||
| DLCO was not included in the multivariate analysis as data on 23 patients were missing. | ||||
| Men | 1.3 (0.64.to 2.62) | 0.47 | 1.61 (0.71 to 3.64) | 0.25 |
| Age (per 10 years) | 1.68 (1.19 to 2.36) | 0.003 | 1.72 (1.14 to 2.6) | 0.01 |
| BMI (kg/m2) | 0.96 (0.9 to 1.03) | 0.3 | 0.91 (0.8 to 1.05) | 0.21 |
| FFMI (kg/m2) | 0.96 (0.82 to 1.11) | 0.58 | 1.08 (0.81 to 1.45) | 0.6 |
| FEV1 (% predicted) | 0.99 (0.97 to 1.01) | 0.17 | 0.98 (0.96 to 1.01) | 0.13 |
| DLCO (%) | 0.97 (0.95 to 0.99) | 0.016 | ||
| QMVC (10% of BMI) | 0.92 (0.85 to 0.99) | 0.022 | 0.91 (0.83 to 0.99) | 0.036 |
| Currently smoking | 1.79 (0.82 to 3.93) | 0.14 | 2.06 (0.85 to 5) | 0.11 |
| Pulmonary rehabilitation | 0.95 (0.5 to 1.8) | 0.88 | 1.57 (0.75 to 3.3) | 0.23 |