Annual isolation prevalence of pulmonary non-tuberculous mycobacteria (NTM) and reported tuberculosis cases in Ontario, 1997–2003
| Year | Ontario population* (thousands) | Prevalence¶ (total cases) | |||||
|---|---|---|---|---|---|---|---|
| M aviumcomplex | M xenopi | Rapidly growing mycobacteria† | M kansasii | All species‡ | Tuberculosis§ | ||
| Prevalence calculated as the number of cases per 100 000 Ontario population in a given year. | |||||||
| N/A, not applicable. | |||||||
| *Values for 1999–2003 from Statistics Canada (http://www.statcan.ca/english/Pgdb/demo02.htm, accessed 2004/10/04); values for 1997 and 1998 estimated by back extrapolation. | |||||||
| †M abscessus, M chelonae and M fortuitum. | |||||||
| ‡Data for M avium complex, M xenopi, M fortuitum, M chelonae, M abscessus and M kansasii combined. | |||||||
| §Total number of tuberculosis cases from Public Health and Epidemiology Reports Ontario;15,16 rate calculated according to population from Statistics Canada. | |||||||
| ¶Prevalence of NTM species defined as the isolation prevalence and prevalence of tuberculosis defined according to reported cases of tuberculosis. | |||||||
| **p Value for comparing prevalence over time using generalised linear models with a negative binomial distribution. | |||||||
| 1997 | 11168.4 | 5.6 (629) | 2.6 (293) | 1.2 (134) | 0.09 (10) | 9.1 (1020) | 6.9 (776) |
| 1998 | 11336.0 | 6.1 (688) | 2.1 (241) | 1.4 (156) | 0.17 (19) | 9.4 (1064) | 6.5 (741) |
| 1999 | 11506.4 | 7.2 (824) | 3.4 (388) | 1.4 (165) | 0.17 (20) | 11.8 (1360) | 6.0 (696) |
| 2000 | 11685.4 | 7.6 (892) | 3.3 (389) | 1.7 (194) | 0.22 (26) | 12.5 (1465) | 6.0 (696) |
| 2001 | 11897.6 | 9.4 (1115) | 4.0 (474) | 2.0 (240) | 0.32 (38) | 15.0 (1780) | 5.8 (688) |
| 2002 | 12096.6 | 9.9 (1196) | 4.7 (571) | 2.3 (282) | 0.35 (42) | 16.5 (1991) | 5.6 (677) |
| 2003 | 12238.3 | 8.4 (1027) | 4.2 (513) | 2.0 (240) | 0.23 (28) | 14.1 (1734) | 5.4 (657) |
| Mean annual change (%) | N/A | 7.7 | 11.3 | 9.6 | 23.1 | 8.4 | −4.0 |
| p Value** | _ | <0.0001 | <0.0001 | <0.0001 | 0.001 | <0.0001 | <0.0001 |