Table 3

 Association between immunisation and childhood atopic diseases: ORs adjusted for sex, birthplace, history of bacterial infection, parental smoking, parental asthma, history of viral infection, birth order and history of pneumonia

OutcomeVaccineOR (95% CI)p Value
Asthma by age 7 yearsDiphtheria1.33 (1.06 to 1.68)0.01
Tetanus1.16 (0.94 to 1.43)0.16
Pertussis1.19 (0.96 to 1.47)0.11
Polio1.05 (0.83 to 1.32)0.69
Smallpox0.94 (0.75 to 1.19)0.62
Asthma by age 13 yearsDiphtheria1.28 (0.98 to 1.66)0.07
Tetanus1.18 (0.89 to 1.55)0.24
Pertussis1.11 (0.91 to 1.37)0.31
Polio1.03 (0.79 to 1.35)0.84
Smallpox1.08 (0.90 to 1.29)0.39
Eczema by age 7 yearsDiphtheria1.53 (1.13 to 2.07)<0.01
Tetanus1.53 (1.15 to 2.04)<0.01
Pertussis1.46 (1.10 to 1.93)<0.01
Polio1.36 (1.00 to 1.87)0.05
Smallpox0.95 (0.73 to 1.23)0.69
Food allergy by age 7 yearsDiphtheria1.47 (1.04 to 2.07)0.03
Tetanus1.26 (0.93 to 1.71)0.14
Pertussis1.39 (1.01 to 1.91)0.04
Polio1.44 (1.00 to 2.07)0.05
Smallpox1.18 (0.88 to 1.58)0.28
Hay fever by age 7 yearsDiphtheria1.20 (0.94 to 1.53)0.15
Tetanus1.05 (0.84 to 1.31)0.67
Pertussis1.10 (0.88 to 1.38)0.42
Polio0.88 (0.69 to 1.12)0.30
Smallpox1.07 (0.85 to 1.34)0.59