Baseline characteristics in the histological patterns of idiopathic pulmonary fibrosis
| Variables | |||
|---|---|---|---|
| Minimal fibrosis | Moderate fibrosis | Several fibrosis | |
| CS, clinical score; F, female; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; HRCT, high-resolution computed tomography; IPF, idiopathic interstitial pneumonia; LOD, level of dyspnoea; M, male; Paco2, partial arterial pressure of carbon dioxide; Pao2, partial arterial pressure of oxygen; RV, residual volume; pr, predicted; TLC, total lung capacity; Tlco, carbon monoxide transfer factor; VA, alveolar volume. | |||
| Data are presented as means (SEM). | |||
| Age at biopsy (years) | 62.2 (7.4) | 63.5 (8.6) | 67.5 (7.8) |
| Sex (F/M) | 5/10 | 7/11 | 8/14 |
| Dyspnoea | |||
| LOD | 8 (4) | 10 (2) | 12 (2) |
| Spirometry | |||
| FEV1 (% pr) | 74 (18) | 66 (20) | 90 (27) |
| FVC (% pr) | 66 (18) | 59 (17) | 76 (23) |
| FEV1/FVC | 87 (8) | 72 (34) | 90 (10) |
| TLC (% pr) | 67 (14) | 70 (84) | 76 (21) |
| RV (% pr) | 74 (15) | 78 (46) | 90 (46) |
| RV/TLC (% pr) | 43 (9) | 46 (17) | 44 (14) |
| Tlco (% pr) | 44 (17) | 54 (28) | 48 (22) |
| Tlco/VA(% pr) | 45 (17) | 52 (12) | 60 (20) |
| Pao2 (kPa) | 8.9 (1.7) | 8.4 (1.5) | 8.8 (1.9) |
| Paco2 (kPa) | 4.8 (0.7) | 4.8 (0.4) | 5.1 (0.5) |
| HRCT score | |||
| Alveolar | 1.7 (0.22) | 1.75 (0.4) | 1.8 (0.5) |
| Interstitial | 1.85 (0.61) | 1.87 (0.42) | 1.89 (0.56) |
| Total | 3.55 (0.83) | 3.52 (0.82) | 3.69 (1.06) |
| Total CS | 50 (20) | 52 (26) | 53 (12) |