Table 4 Longitudinal analyses of the association between decline in FEV1 from age 26 to 32 and CRP at age 26 and 32
OutcomePredictorCovariatesnCoefficient (95% CI)p Value
Fall in FEV1 (ml)Age 26 log-CRPSex, height766−3.30 (−25.1 to 18.5)0.77
Sex, height, smoking*, asthma*765−2.55 (−24.4 to 19.3)0.82
Age 32 log-CRPFall in FEV1 (litres)Sex, height7880.48 (0.25 to 0.71)<0.001
Sex, height, smoking*, asthma*, age 26 CRP7390.49 (0.26 to 0.71)<0.001
  • CRP, C-reactive protein; FEV1, forced expiratory volume in one second.

  • CRP values were log transformed for analysis and are expressed as standard deviation scores. Analyses exclude women who were pregnant at either age. *Analyses adjusted for history of smoking between age 26 and 32 years and current asthma diagnosis at either age.