| No asthma | Lifetime asthma | Current asthma | Early persistent asthma (diagnosis by 3 years) | Late onset asthma (diagnosis after 3 years) | |||||
| N | N | OR* (95% CI) | N | OR* (95% CI) | N | OR* (95% CI) | N | OR* (95% CI) | |
| EPHX1 Tyr113His | |||||||||
| Tyr/Tyr | 1253 | 241 | 1.0 | 154 | 1.0 | 89 | 1.0 | 126 | 1.0 |
| Tyr/His | 1112 | 189 | 0.86 (0.69 to 1.07) | 124 | 0.87 (0.67 to 1.12) | 62 | 0.81 (0.57 to 1.15) | 99 | 0.83 (0.62 to 1.10) |
| His/His | 283 | 46 | 0.79 (0.55 to 1.13) | 30 | 0.79 (0.51 to 1.22) | 24 | 1.21 (0.74 to 1.97) | 16 | 0.51 (0.29 to 0.88) |
| EPHX1 His139Arg | |||||||||
| His/His | 1817 | 290 | 1.0 | 186 | 1.0 | 112 | 1.0 | 140 | 1.0 |
| His/Arg | 741 | 174 | 1.42 (1.14 to 1.76) | 114 | 1.45 (1.12 to 1.89) | 57 | 1.25 (0.89 to 1.78) | 96 | 1.58 (1.19 to 2.10) |
| Arg/Arg | 90 | 12 | 0.78 (0.41 to 1.47) | 8 | 0.81 (0.38 to 1.76) | 6 | 0.94 (0.38 to 2.31) | 5 | 0.68 (0.26 to 1.73) |
| GSTP1 Ile105Val† | |||||||||
| Ile/Ile | 1043 | 171 | 1.0 | 116 | 1.0 | 57 | 1.0 | 93 | 1.0 |
| Ile/Val | 1229 | 230 | 1.17 (0.94 to 1.47) | 146 | 1.08 (0.82 to 1.41) | 85 | 1.37 (0.95 to 1.96) | 116 | 1.08 (0.81 to 1.46) |
| Val/Val | 343 | 65 | 1.31 (0.94 to 1.81) | 38 | 1.14 (0.76 to 1.70) | 29 | 1.95 (1.19 to 3.18) | 26 | 0.93 (0.58 to 1.49) |
*ORs adjusted for age, sex, race/ethnicity, in utero exposure to maternal smoking, number of smokers at home, community of residence, parental education, health insurance and parental history of asthma.
†Data on GSTP1 Ile105Val genotype were unavailable for 43 children.