Univariate logistic regression
| Without OSA (n = 29)* | With OSA (n = 14)* | OR (95% CI) | p Value | |
|---|---|---|---|---|
| FEV1, forced expiratory volume in the first second; OSA, obstructive sleep apnoea; SaO2, oxygen saturation; %TST with SaO2 <90%: percentage of total sleep time with oxygen saturation <90%. | ||||
| *Values are median (IQR) unless otherwise mentioned. | ||||
| Tonsil size, left | 1.0 (1.0–2.0) | 2.0 (1.0–3.0) | 1.51 (0.91 to 2.48) | 0.110 |
| Tonsils size, right | 1.0 (0.0–2.0) | 1.5 (1.0–4.0) | 1.62 (0.98 to 2.98) | 0.098 |
| FEV1 (% predicted) | 94.0(87.0–102.5) | 87.0 (82.8–96.0) | 0.96 (0.89 to 1.03) | 0.233 |
| Sputum eosinophils (%) | 2.0 (0.8–4.2) | 0.4 (0.0–3.0) | 0.67 (0.44 to 1.03) | 0.067 |
| Sputum neutrophils (%) | 4.0 (3.0–11.3) | 18.5 (8.0–42.0) | 1.08 (1.02 to 1.16) | 0.014 |
| Sputum macrophages (%) | 84.0 (77.8–89.0) | 76.0 (56.0–87.0) | 0.93 (0.88 to 0.99) | 0.017 |
| %TST with SaO2 <90% | 0.1 (0.0–0.2) | 1.6 (0.2–3.7) | 1.79 (1.01 to 3.18) | 0.046 |
| SaO2 nadir (%) | 90.5 (84.3–93.0) | 82.0 (72.0–87.0) | 0.87 (0.78 to 0.96) | 0.004 |
| Arousal index | 5.7 (4.4–8.3) | 9.1 (6.8–15.3) | 1.25 (1.04 to 1.51) | 0.020 |
| Asthma, yes/no (n) | 10/19 | 2/12 | 3.18 (0.59 to 16.96) | 0.180 |