Table 4

 Cost-effectiveness analyses

No evaluationLimited evaluation
CER, cost effectiveness ratio; NNT, number needed to treat.
*Assuming 400 CAP admissions per year.
†Cost per additional patient receiving appropriate antibiotics within 4 h.
Intervention costs (design, implementation and evaluation)£4841£17 809
Adjusted net difference in cost of first dose of antibiotics£443 (95% CI £209 to £675)
Total net costs£5284£18 252
Additional patients receiving appropriate antibiotics within 4 h40 (95% CI 19 to 63)
Cost per additional patient receiving appropriate antibiotics within 4 h
CER£132£456
Sensitivity analyses
CER with 95% CI for effect
    Lower£278£961
    Upper£84£290
CER for project over time*
    1 year£91£254
    3 years£60£111
    5 years£54£82
Cost per death prevented
    Number of additional patients who need to receive antibiotics within 4 h to prevent one death42 (95% CI 26 to 129)
    Estimated cost saving based on a 0.4-day reduction in mean length of stay (excluding patients who died)£2424
    Total net costs£2860£15 828
CER†£71.50£396
CER using lower 95% CI for effect£150.50£833
CER using upper 95% CI for effect£45£251
Cost per death prevented£3003£16 632
Range for cost per death prevented using sensitivity analyses for cost per additional patient receiving appropriate antibiotics within 4 h and upper/lower 95% CI for NNT£1170 to £19 414£6526 to £107 457