Cost-effectiveness analyses
No evaluation | Limited evaluation | |
---|---|---|
CER, cost effectiveness ratio; NNT, number needed to treat. | ||
*Assuming 400 CAP admissions per year. | ||
†Cost per additional patient receiving appropriate antibiotics within 4 h. | ||
Intervention costs (design, implementation and evaluation) | £4841 | £17 809 |
Adjusted net difference in cost of first dose of antibiotics | £443 (95% CI £209 to £675) | |
Total net costs | £5284 | £18 252 |
Additional patients receiving appropriate antibiotics within 4 h | 40 (95% CI 19 to 63) | |
Cost per additional patient receiving appropriate antibiotics within 4 h | ||
CER | £132 | £456 |
Sensitivity analyses | ||
CER with 95% CI for effect | ||
Lower | £278 | £961 |
Upper | £84 | £290 |
CER for project over time* | ||
1 year | £91 | £254 |
3 years | £60 | £111 |
5 years | £54 | £82 |
Cost per death prevented | ||
Number of additional patients who need to receive antibiotics within 4 h to prevent one death | 42 (95% CI 26 to 129) | |
Estimated cost saving based on a 0.4-day reduction in mean length of stay (excluding patients who died) | £2424 | |
Total net costs | £2860 | £15 828 |
CER† | £71.50 | £396 |
CER using lower 95% CI for effect | £150.50 | £833 |
CER using upper 95% CI for effect | £45 | £251 |
Cost per death prevented | £3003 | £16 632 |
Range for cost per death prevented using sensitivity analyses for cost per additional patient receiving appropriate antibiotics within 4 h and upper/lower 95% CI for NNT | £1170 to £19 414 | £6526 to £107 457 |