Table 1 Univariate and multivariate analysis of 30-day mortality in patients resected for lung cancer 1993–2005 (n = 4395)
NoMortalityUnivariate analysisMultivariate analysis
N (%)OR (95% CI)p ValueOR (95% CI)p Valueβ
Intercept−5.97
Sex<0.0010.003
    Female164741 (2.5)1.00 (reference)1.00 (reference)
    Male2748152 (5.5)2.29 (1.62 to 3.26)1.76 (1.22 to 2.54)0.56
Age (years)<0.001<0.001
    <503809 (2.4)1.00 (reference)1.00 (reference)
    50–5992422 (2.4)1.01 (0.50 to 2.20)1.04 (0.47 to 2.30)0.038
    60–69148751 (3.4)1.46 (0.71 to 3.00)1.59 (0.77 to 3.30)0.47
    70–79147193 (6.3)2.78 (1.39 to 5.57)3.38 (1.66 to 6.89)1.22
    80–8913318 (13.5)6.45 (2.82 to 14.75)9.94 (4.17 to 23.69)2.30
Side of resection<0.0010.001
    Left199163 (3.2)1.00 (reference)1.00 (reference)
    Right2404130 (5.4)1.75 (1.29 to 2.38)1.73 (1.24 to 2.41)0.55
Surgical approach0.120.39
    VATS1322 (1.5)1.00 (reference)1.00 (reference)
    Open thoracotomy4263191 (4.5)3.05 (0.75 to 12.41)1.88 (0.44 to 7.97)0.63
Surgical procedure<0.001<0.001
    Upper lobectomy152030 (2.0)1.00 (reference)1.00 (reference)
    Middle lobectomy1242 (1.6)0.82 (0.19 to 3.46)0.61 (0.14 to 2.61)−0.50
    Lower lobectomy101935 (3.4)1.72 (1.05 to 2.83)1.52 (0.92 to 2.52)0.42
    Bilobectomy38328 (7.3)3.92 (2.31 to 6.65)3.06 (1.76 to 5.34)1.12
    Pneumonectomy107192 (8.6)4.66 (3.06 to 7.10)4.54 (2.87 to 7.18)1.51
    Sublobar resection2786 (2.2)1.14 (0.47 to 2.76)0.92 (0.37 to 2.26)−0.086
Histopathology type0.0250.27
    Adenocarcinoma186564 (3.4)1.00 (reference)1.00 (reference)
    Squamous cell156583 (5.3)1.58 (1.13 to 2.20)1.08 (0.75 to 1.55)0.078
    Other96546 (4.8)1.41 (0.96 to 2.07)1.38 (0.92 to 2.08)0.32
Pathological stage<0.0010.066
    I2856103 (3.6)1.00 (reference)1.00 (reference)
    II101854 (5.3)1.50 (1.07 to 2.10)1.15 (0.81 to 1.65)0.14
    III42825 (5.8)1.66 (1.06 to 2.60)1.24 (0.77 to 2.00)0.21
    IV9311 (11.8)3.59 (1.85 to 6.93)2.67 (1.29 to 5.54)0.98
Hospital volume0.0530.076
    <20147677 (5.2)1.00 (reference)1.00 (reference)
    ⩾202919116 (4.0)0.75 (0.56 to 1.00)0.76 (0.56 to 1.03)−0.28
Tumour size (cm)0.0020.84
    ⩽3187761 (3.2)1.00 (reference)1.00 (reference)
    >3–5140962 (4.4)1.37 (0.96 to 1.97)0.93 (0.64 to 1.36)−0.073
    >5104366 (6.3)2.01 (1.41 to 2.87)1.10 (0.74 to 1.62)0.095
    Unknown664 (6.1)1.92 (0.68 to 5.45)1.16 (0.39 to 3.40)0.14
  • OR, odds ratio; CI, confidence interval; β, coefficient beta; VATS, video assisted thoracic surgery.