Clinical and microbiological features of patients from whom NTM were isolated before (n = 26) and/or after (n = 20) transplantation
| Sex | Age | Pre-transplant NTM | Post-transplant NTM | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Species | Source | AFB smear | Time of isolation (months before Tx) | Species | Source | AFB smear | Time to isolation (months after Tx) | BOS stage | Disease | Follow up after NTM isolation (months) | Survival after transplant (months) | |||
| *Persistently cultured NTM on >10 occasions. | ||||||||||||||
| AFB, acid fast bacilli; MAC, Mycobacterium avium complex; BAL, bronchoalveolar lavage; Tx, transplant. | ||||||||||||||
| 1 | F | 22 | M abscessus | Sputum | ++ | 3, 33 | M abscessus | Wound, blood | + | 4, 4, 5, 6 | 0 | Yes | 90 | 94 |
| 2 | M | 32 | M abscessus | Sputum | +++ | 4, 11 | M abscessus | Wound swab | +++ | 3, 4, 4 | 0 | Yes | 50 | 53 |
| 3 | F | 22 | MAC | Sputum | – | 12 | MAC | Sputum, BAL | ++ | 38, 41 | 3 | Yes | 6 | 44 |
| M szulgai | Sputum, BAL | ++ | 38, 41 | 3 | ||||||||||
| 4 | M | 29 | Unspecified | Sputum | + | 20 | M kansasii | BAL | ++ | 8, 10, 10 | 0 | Yes | 8 | 19 |
| 5 | F | 19 | MAC | Sputum | – | 14 | MAC | Sputum, BAL | – | 69, 69, 69 | 2 | No | 28 | 97 |
| 6 | F | 17 | MAC | Sputum | – | 21 | M gordonae | BAL | – | 9 | 0 | No | 60 | 69 |
| 7 | M | 25 | MAC | Sputum | – | 42 | MAC | BAL | – | 18 | 0 | No | 24 | 42 |
| M fortuitum | BAL | – | 11, 13, 18 | 0 | No | 31 | ||||||||
| 8 | F | 20 | M abscessus | Sputum | +++ | 1 | Negative | – | – | – | – | – | – | 28 |
| 9 | F | 26 | M abscessus | Sputum, BAL | +++ | Persistent*,29-7 | Negative | – | – | – | – | – | – | 3 |
| 10 | F | 31 | M abscessus | Sputum | ++ | 5, 6 | Negative | – | – | – | – | – | – | 23 |
| 11 | M | 19 | M abscessus | Sputum, BAL | + | 22, 22, 22,24 | Negative | – | – | – | – | – | – | 8 |
| 12 | M | 29 | M abscessus | Sputum | ++ | Persistent*,34-2 | Negative | – | – | – | – | – | – | 21 |
| 13 | F | 27 | MAC | Sputum | – | 13 | Negative | – | – | – | – | – | – | 23 |
| 14 | F | 36 | MAC | Sputum | + | 26, 38 | Negative | – | – | – | – | – | – | 0 |
| 15 | M | 41 | MAC | Sputum, BAL | +++ | Persistent*,41-7 | Negative | – | – | – | – | – | – | 62 |
| 16 | F | 18 | M gordonae | Sputum | - | 31 | Negative | – | – | – | – | – | – | 19 |
| 17 | M | 32 | MAC | Sputum | N/A | 9 | Negative | – | – | – | – | – | – | 18 |
| M chelonei abscessus | Sputum | N/A | 6 | |||||||||||
| 18 | M | 22 | MAC | Sputum | + | 34, 36 | Negative | – | – | – | – | – | – | 62 |
| M fortuitum | Sputum | – | 41 | |||||||||||
| 19 | M | 25 | M abscessus | Sputum | ++ | On Tx list | – | – | – | – | – | – | – | N/A |
| 20 | F | 14 | M abscessus | Sputum | +++ | On Tx list | – | – | – | – | – | – | – | N/A |
| 21 | M | 48 | M abscessus | Sputum | +++ | On Tx list | – | – | – | – | – | – | – | N/A |
| 22 | M | 35 | MAC | Sputum | – | On Tx list | – | – | – | – | – | – | – | N/A |
| 23 | M | 38 | MAC | Sputum | – | On Tx list | – | – | – | – | – | – | – | N/A |
| 24 | M | 49 | MAC | Sputum | – | On Tx list | – | – | – | – | – | – | – | N/A |
| 25 | F | 43 | M abscessus | Sputum | +++ | On Tx list | – | – | – | – | – | – | – | N/A |
| MAC | Sputum | – | ||||||||||||
| 26 | M | 33 | M gordonae | Sputum | – | On Tx list | – | – | – | – | – | – | – | N/A |
| 27 | F | 13 | Negative | Sputum | – | – | MAC | BAL | – | 4 | 0 | No | 25 | 29 |
| 28 | F | 26 | Negative | Sputum | – | – | MAC | BAL | – | 35 | 3 | No | 4 | 39 |
| 30 | M | 33 | Negative | Sputum | – | – | MAC | BAL | – | 18 | 0 | No | 54 | 72 |
| 29 | M | 21 | Negative | Sputum | – | – | M gordonae | BAL | – | 84 | 2 | No | 5 | 89 |
| 31 | F | 24 | Negative | Sputum | – | – | M gordonae | BAL | – | 10 | 0 | No | 17 | 27 |
| 32 | F | 29 | Negative | Sputum | – | – | M gordonae | BAL | – | Persistent*, 8–31 | 0 | No | 51 | 59 |
| 33 | M | 36 | Negative | Sputum | – | – | M gordonae | BAL | – | 2 | 0 | No | 100 | 102 |
| 34 | M | 46 | Negative | Sputum | – | – | M gordonae | BAL | – | 3 | 0 | No | 77 | 80 |
| 35 | M | 29 | Negative | Sputum | – | – | MAC | BAL | – | 8, 14 | 0 | No | 24 | 32 |
| M gordonae | BAL | – | 26 | 0 | No | 6 | ||||||||
| 36 | M | 29 | Negative | Sputum | – | – | M kansasii | BAL | + | 1 | 0 | No | 33 | 34 |
| 37 | M | 31 | Unknown | N/A | N/A | N/A | MAC | Sputum | – | 117 | 2 | No | 7 | 124 |
| 38 | F | 24 | Unknown | N/A | N/A | N/A | MAC | BAL, wash | – | 101, 105 | 3 | No | 30 | 135 |
| 39 | M | 27 | Unknown | N/A | N/A | N/A | M abscessus | Sputum, BAL | – | 57 | 3 | Yes | 13 | 69 |