Therapy | Evidence | Data limitations and considerations |
---|---|---|
Asthma type therapy | ||
Inhaled beta2-agonists | SR | Non-beneficial; only 1 small RCT |
Mast cell stabilisers | SR | No RCT; single cohort study only |
Methylxanthines | SR | No RCT; adverse events |
Anticholinergics | SR | No RCT |
Inhaled corticosteroids | SR | RCT = 2; non-beneficial; high placebo effect; adverse events |
Gastro-oesophageal reflux treatment | SR | RCT = 3; data inconclusive |
Anti-microbials | No RCT | SR in chronic ‘wet’cough—some benefit |
Others | No RCT | No data |