Table 1

 Effect of inhaled dust extract on IL-5 and IL-10 production of murine splenocytes

TreatmentIL-5 (pg/ml)IL-10 (pg/ml)
IL, interleukin; PBS, phosphate buffered saline; LPS, lipopolysaccharide.
In vitro production of IL-5 and IL-10 was measured by ELISA after re-stimulation of splenocytes with OVA for 2 days; n⩾8 per group. Results are presented as median with 25–75th percentile in parentheses. Dust extract treated mice were compared with PBS treated mice by the two tailed Mann-Whitney test.
PBS834 (625.5–1002)1459 (1164–1782)
LPS1080 (806.5–1420)1816 (1482–2030)
Dust extract309 (248–402.3)p<0.00011275 (842.8–1742)p = 0.4398
Non-sensitised5.2 (0–16.5)91.5 (78–124)