Non-modifiable risk factors for hospital admission with acute asthma
| Asthma admissions (AA)(n = 84) | Stable asthma (SA)(n = 84) | Inpatient control (IC)(n = 84) | Odds ratio (95% CI)* | p value* | |
|---|---|---|---|---|---|
| *Comparisons of groups (AA v SA; AA v IC): conditional logistic regression. | |||||
| †Median (range) in years. | |||||
| ‡OR refers to decreased risk with each additional year. | |||||
| White ethnicity | 71 (84.5%) | 78 (92.9%) | 75 (89.3%) | AA v SA: 0.5 (0.2 to 1.2) | 0.12 |
| AA v IC: 0.7 (0.3 to 1.6) | 0.37 | ||||
| Maternal asthma | 21 (25.0%) | 33 (39.3%) | 11 (13.1%) | AA v SA: 0.5 (0.3 to 1.0) | 0.06 |
| AA v IC: 2.0 (0.9 to 4.3) | 0.07 | ||||
| Previous hospital asthma admission | 59 (70.2%) | 48 (57.1%) | 0 (0%) | AA v SA: 1.6 (0.9 to 2.8) | 0.12 |
| AA v IC: OR not defined | – | ||||
| Duration of asthma† | 3.1 (0.1–14.7) | 4.7 (0.4–15.2) | – | AA v SA: 0.8 (0.7 to 0.9)‡ | 0.004 |
| AA v IC: OR not defined | – | ||||
| Hay fever | 25 (29.8%) | 29 (34.5%) | 8 (9.5%) | AA v SA: 0.8 (0.4 to 1.5) | 0.51 |
| AA v IC: 3.4 (1.5 to 8.0) | 0.004 | ||||
| Eczema | 48 (57.1%) | 47 (56.0) | 15 (17.9%) | AA v SA: 1.1 (0.6 to 2.0) | 0.87 |
| AA v IC: 7.6 (3.0 to 19.3) | <0.001 | ||||
| Atopy: skin tests | |||||
| At least 1 allergen | 72 (85.7%) | 51 (60.7%) | 26 (31.0%) | AA v SA: 3.6 (1.7 to 7.9) | 0.001 |
| AA v IC: 16.3 (5.1 to 52) | <0.001 | ||||
| House dust mite | 56 (66.7%) | 44 (52.4%) | 23 (27.4%) | AA v SA: 1.8 (0.9 to 3.2) | 0.07 |
| AA v IC: 5.7 (2.6 to 12.8) | <0.001 | ||||
| Cat | 36 (42.9%) | 28 (33.3%) | 4 (4.8%) | AA v SA: 1.6 (0.8 to 3.1) | 0.19 |
| AA v IC: 17 (4.1 to 71.0) | <0.001 | ||||
| Dog | 32 (38.1%) | 17 (20.2%) | 2 (2.4%) | AA v SA: 2.4 (1.2 to 4.8) | 0.017 |
| AA v IC: OR not defined | <0.001 | ||||
| Pollen | 48 (57.1%) | 40 (47.6%) | 16 (19.0%) | AA v SA: 1.5 (0.8 to 2.9) | 0.20 |
| AA v IC: 9.0 (3.2 to 25.3) | <0.001 | ||||
| Atopy: IgE (GM and range; kU/l) | |||||
| Total IgE | 438.8 | 183.4 | 55.7 | AA v SA:1.20 (0.94 to 1.53) | 0.14 |
| (5.0–6036) | (2.0–9775) | (2.0–4905) | AA v IC: 1.77 (1.29 to 2.43) | <0.001 | |
| Specific IgE mite | 20.3 | 5.2 | 0.79 | AA v SA: 1.13 (0.98 to 1.30) | 0.09 |
| (0.35–955) | (0.35–988) | (0.35–251) | AA v IC: 1.59 (1.23 to 2.06) | <0.001 | |
| Specific IgE cat | 1.64 | 1.0 | 0.39 | AA v SA: 1.09 (0.90 to 1.32) | 0.40 |
| (0.35–177) | (0.35–356) | (0.35–6.53) | AA v IC: 2.64 (1.20 to 5.81) | 0.016 | |
| Specific IgE dog | 2.3 | 1.2 | 0.40 | AA v SA: 1.09 (0.89 to 1.32) | 0.40 |
| (0.35–654) | (0.35–366) | (0.35–13.5) | AA v IC: 2.20 (1.25 to 3.89) | 0.007 | |
| Specific IgE rye | 3.6 | 2.2 | 0.53 | AA v SA: 1.03 (0.87 to 1.22) | 0.76 |
| (0.5–959) | (0.35–428) | (0.35–187) | AA v IC: 1.73 (1.17 to 2.57) | 0.006 | |