Comparison of lung function and C-reactive protein (CRP) levels between rhinovirus, Bordetella pertussis, Chlamydia pneumoniae positive and negative asthma patients
| N | FEV1(l/s) | FEV1 (% predicted) | FEV1/FVC (%) | FEV1/FVC (% predicted) | CRP (mg/l) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Median(range) | Median difference(95% CI) | Median(range) | Median difference(95% CI) | Median(range) | Median difference(95% CI) | Median(range) | Median difference(95% CI) | Median(range) | Median difference(95% CI) | ||
| CI, confidence interval; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity. | |||||||||||
| *Mann-Whitney U test, two tailed asymptomatic significance. | |||||||||||
| †Statistically significant. | |||||||||||
| Rhinovirus | |||||||||||
| Positive | 13 | 2.79 (2.03–3.57) | −0.23 (−0.61 to 0.18) | 79 (58–111) | −10.0 (−18.0 to −2.0) | 80.5 (72.0–88.3) | 1.0 (−2.3 to 4.3) | 98 (82–105) | 1.0 (−3.5 to 5.0) | 3.31 (0.86–12.11) | 1.04 (−0.18 to 2.75) |
| Negative | 90 | 3.03 (1.59–5.52) | 93.5 (40–130) | 80.0 (47.6–91.4) | 97 (67–110) | 1.96 (0.01–24.41) | |||||
| p value* | 0.243 | 0.020‡ | 0.568 | 0.651 | 0.092 | ||||||
| B pertussis | |||||||||||
| Positive | 25 | 2.93 (1.69–5.47) | −0.05 (−0.38 to 0.31) | 93 (40–127) | 0.0 (−8.0 to 8.0) | 78.4 (47.6–87.9) | −2.5 (−5.5 to 0.5) | 95 (67–109) | −2.0 (−6.1 to 2.0) | 2.21 (0.07–24.41) | 0.35 (−0.59 to 1.37) |
| Negative | 78 | 2.99 (1.59–5.52) | 92 (57–130) | 80.4 (60.2–91.4) | 97 (72–110) | 2.07 (0.01–19.65) | |||||
| p value* | 0.838 | 0.926 | 0.105 | 0.3 | 0.472 | ||||||
| C pneumoniae | |||||||||||
| Positive | 22 | 2.94 (1.81–4.41) | 0.03 (−0.32 to 0.35) | 89 (58–127) | −4.0 (−11.0 to 4.0) | 78.2 (61.2–89.5) | −3.5 (−6.1 to −0.4) | 94 (74–110) | −3.9 (−7.0 to 0.0) | 2.47 (0.07–7.31) | −0.17 (−1.09 to 0.94) |
| Negative | 81 | 2.94 (1.59–5.54) | 92 (40–130) | 80.8 (47.6–91.4) | 98 (67–110) | 2.01 (0.01–24.41) | |||||
| p value* | 0.888 | 0.376 | 0.023† | 0.041† | 0.815 | ||||||