Table 4

 Pooled odds ratios for TNFα-308 gene polymorphism and asthma susceptibility in meta-analyses: comparisons of alleles and genotypes

ComparisonNo of studiesOR (95% CI)p value*Publication biasHeterogeneity test†
OR, odds ratio; CI, confidence interval.
*Random effects models were used, weighted by the inverse variance. All statistical tests are two sided.
†p<0.1 is considered statistically significant for Q statistics; I2 is interpreted as the proportion of total variation contributed by between-study variation; H<1.2 suggests no heterogeneity among studies.
TNF2 v TNF1141.37 (1.02 to 1.84)0.04p>0.2p>0.2<0.010.751.98
TNF2/2 v TNF1/182.01 (1.26 to 3.20)0.009p>0.2p>0.20.0290.531.46
TNF2/2 v TNF2/181.51 (1.02 to 2.22)0.041p>0.2p>0.2>0.101
TNF2/1 v TNF1/1111.47 (1.01 to 2.13)0.045p>0.2p = 0.04<0.010.741.97