Subject characteristics
| Measured value | % Predicted | |
|---|---|---|
| Values are mean (SE). | ||
| *Predicted maximum exercise values from Jones.24 | ||
| †V̇e expressed as % of estimated maximal ventilatory capacity (35 × FEV1). | ||
| EV, expiratory volume; FEV1, forced expired volume in 1 second; FVC, forced vital capacity; Pimax, maximal inspiratory pressure; PEFR, peak expiratory flow rate; RV, residual volume; Sao2, oxygen saturation; TLC, total lung capacity; FRCpl, plethysmographic functional residual capacity; IC, inspiratory capacity; Tlco/Va, transfer factor of the lung for carbon monoxide corrected for alveolar volume; V̇e, minute ventilation; V̇o2, oxygen consumption; IRV, inspiratory reserve volume. | ||
| Sex (M:F) | 9:7 | |
| Age (years) | 62 (2) | |
| Height (cm) | 168 (2) | |
| Weight (kg) | 75.8 (3.8) | |
| Body mass index (kg/m2) | 26.8 (1.1) | |
| Smoking history (pack years) | 50 (7) | |
| Duration of COPD (years) | 9 (2) | |
| Pulmonary function | ||
| FEV1 (l) | 1.16 (0.10) | 43 (3) |
| FVC (l) | 2.66 (0.19) | 71 (4) |
| FEV1/FVC (%) | 43.9 (1.9) | 62 (3) |
| PEFR (l/s) | 4.02 (0.26) | 56 (4) |
| TLC (l) | 6.74 (0.28) | 114 (4) |
| RV (l) | 3.66 (0.21) | 174 (10) |
| FRCpl (l) | 4.73 (0.21) | 150 (6) |
| IC (l) | 2.01 (0.15) | 72 (4) |
| Pimax (cm H2O) | 56 (5) | 72 (7) |
| Tlco/Va (ml/min/mm Hg/l) | 3.31 (0.17) | 87 (5) |
| Peak incremental exercise* | ||
| Work rate (W) | 78 (8) | 55 (3) |
| Heart rate (beats/min) | 120 (4) | 71 (2) |
| V̇o2 (l/min) | 1.16 (0.12) | 62 (4) |
| V̇e (l/min) | 38.5 (2.9) | 98 (5)† |
| EILV/TLC (%) | 94 (1) | |
| IRV (l) | 0.37 (0.07) | |
| Sao2 (%) | 93 (1) | |
| Dyspnoea (Borg scale) | 5.4 (0.5) “severe” | |
| Leg discomfort (Borg scale) | 5.1 (0.5) “severe” | |