Lung function and body composition of patients with normal and raised levels of CRP
| Normal CRP(n = 54) | Raised CRP(n = 48) | p value | |
|---|---|---|---|
| Values are mean (SD) unless stated otherwise. | |||
| BMI, body mass index; FFMI, fat-free mass index; FM, fat mass; FEV1, forced expiratory volume in 1 second; pre, pre-bronchodilator; post, post-bronchodilator; FVC, forced vital capacity; Tlco, carbon monoxide transfer factor; Pao2, arterial oxygen tension; Paco2, carbon dioxide tension. | |||
| *Median (range) non-parametrically tested with Mann-Whitney U test. | |||
| M/F | 34/20 | 37/11 | 0.122 |
| Age (years) | 61.3 (10.2) | 64.7 (8.0) | 0.062 |
| Smoking history* | 30.0 (0–80) | 35.0 (0–125) | 0.777 |
| Body composition | |||
| BMI (kg/m2) | 21.9 (4.1) | 22.8 (3.3) | 0.209 |
| FFMI (kg/m2) | 15.8 (2.1) | 16.1 (1.7) | 0.363 |
| FM (%) | 27.0 (7.8) | 28.9 (6.3) | 0.191 |
| Lung function | |||
| FEV1 (pre) (% predicted) | 35.9 (14.3) | 33.1 (12.4) | 0.294 |
| FEV1 (post) (% predicted) | 39.9 (15.3) | 33.8 (12.2) | 0.031 |
| FVC (% predicted) | 78.0 (17.9) | 75.3 (18.7) | 0.472 |
| Reversibility (% predicted)* | 2.9 (−8.3–13.0) | 0.0 (−7.2–8.7) | 0.001 |
| FEV1/FVC (%) | 36 (9) | 35 (9) | 0.366 |
| Tlco (% predicted) | 50.7 (19.7) | 47.4 (20.2) | 0.423 |
| Pao2 (kPa) | 9.34 (1.26) | 9.17 (1.15) | 0.460 |
| Paco2 (kPa) | 5.49 (0.87) | 5.48 (0.87) | 0.538 |