Table 2

 Anti-P aeruginosa antibodies in patients with CF correlated with P aeruginosa status defined retrospectively

Antibodies againstP aeruginosa status according to culture resultsComparison* (p values)
Free (F)(N = 68)Intermittent (I)(N = 27)Chronic (C)(N = 88)F v II v CC v F
Antibody titres were scored as 0 (titre negative <1:500) and 1 (titre positive >1:500).
*Mann-Whitney test for comparison of antibody levels and Fisher’s exact test for comparison of frequency of patients with antibody score ⩾1, corrected for multiple comparisons by Bonferroni method.
Alkaline protease (AP)
Frequency of antibody positive (n/N)1/687/2766/88<0.001<0.001<0.001
Elastase (E)
Frequency of antibody positive (n/N)0/684/2757/88<0.001<0.001<0.001
Exotoxin A (EA)
Frequency of antibody positive (n/N)3/6811/2773/88<0.001<0.001<0.001
Cumulative score (AP/E/EA)
Frequency of antibody score ⩾1 (n/N)3/6813/2786/88<0.001<0.001<0.001