Lung function in betamethasone and placebo exposed participants at age 30
| Betamethasone(n = 181) | Placebo(n = 202) | Difference between groups | p value | |
|---|---|---|---|---|
| FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; PEF, peak expiratory flow; F50, F25, flow at 50% and 25% of forced expiratory flow; FEF25–75, mean forced expiratory flow between 25% and 75%. | ||||
| Data are mean (SD) or n (%). Differences between groups are differences between means (95% CI) or relative risk (95% CI). | ||||
| Data are percentage predicted adjusted for sex and height.11 | ||||
| Mean FVC | 105.9 (12.0) | 106.6 (12.6) | −0.7 (−3.2 to 1.8) | 0.59 |
| Mean FEV1 | 98.9 (13.4) | 98.5 (13.6) | 0.3 (−2.4 to 3.1) | 0.80 |
| Mean FEV1/FVC | 0.80 (0.08) | 0.79 (0.08) | 0.01 (−0.01 to 0.02) | 0.48 |
| Mean PEF | 101.3 (14.3) | 99.1 (15.4) | 2.2 (−0.8 to 5.2) | 0.15 |
| Mean F50 | 80.1 (23.2) | 77.1 (22.3) | 3.0 (−1.5 to 7.6) | 0.19 |
| Mean F25 | 64.0 (20.5) | 63.6 (21.6) | 0.4 (−3.8 to 4.7) | 0.84 |
| Mean FEF25–75% | 74.9 (21.6) | 72.7 (21.3) | 2.2 (−2.1 to 6.5) | 0.31 |
| FEV1/FVC <70% | 18 (10) | 23 (11) | 0.87 (0.49 to 1.57) | 0.65 |