Immunoreactive Trx associated with various cell types in autopsy and biopsy lung specimens from patients with ALI/ARDS and controls
| ALI/ARDS patients(n = 10) | Control patients(n = 9) | Mann-Whitney test | |
|---|---|---|---|
| Data are presented as median score with interquartile range in parentheses; groups were compared by the Mann-Whitney U test. | |||
| Intensity of staining was quantified using a semi-quantitative point score (0–5 in 0.5 intervals) by an observer blinded to the identity of the slides. | |||
| *N/A = not applicable because the Mann-Whitney test is unable to analyse differences between groups when all variables in one group are zero. | |||
| Alveolar macrophages | 3.25 (2.25–4.0) | 2.0 (1.5–2.0) | p = 0.0021 |
| Type II alveolar epithelial cells | 2.25 (1.0–3.0) | 1.0 (0.5–1.0) | p = 0.0057 |
| Endothelial cells | 0 (0–0) | 0 (0–0) | N/A* |
| Interstitial lymphocytes | 0 (0–0) | 0 (0–0) | N/A* |
| Interstitial fibroblasts | 0 (0–0.5) | 0 (0–0) | N/A* |
| Neutrophils | 0 (0–0) | 0 (0–0) | N/A* |
| Bronchial epithelial cells | 2.0 (1.0–3.0) | 2.0 (1.0–2.5) | p = 0.918 |
| Interstitial macrophages | 1.0 (0–2.0) | 2.0 (0–2.0) | p = 0.106 |