Baseline characteristics of study patients
| Children | Adults | |
|---|---|---|
| FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; MEF25, MEF50, mid expiratory flow at 25% and 50% of vital capacity; RV, residual volume; TLC, total lung capacity. | ||
| Data are given as mean (SD). | ||
| Age (years) | 11 (4) | 28 (8) |
| Sex (M/F) | 37/35 | 24/23 |
| Pancreatic status (sufficient/insufficient) | 11/61 | 14/33 |
| Chronic Pseudomonas infection (yes/no) | 14/58 | 18/29 |
| FVC (% predicted) | 97 (18) | 94 (19) |
| FEV1 (% predicted) | 97 (21) | 78 (24) |
| RV (% predicted) | 98 (42) | 126 (47) |
| TLC (% predicted) | 95 (18) | 102 (12) |
| MEF50 (% predicted) | 96 (34) | 51 (30) |
| MEF25 (% predicted) | 84 (46) | 41 (33) |
| FEV1/FVC (%) | 88 (9) | 70 (13) |
| FEV1/FVC (% predicted) | 98 (10) | 84 (16) |
| RV/TLC (%) | 26 (11) | 33 (13) |
| RV/TLC (% predicted) | 104 (43) | 120 (42) |
| Composite CT score (points, %) | 9 (11) | 17 (13) |