Table 4

 Association between SFRS8 haplotypes and asthma

HaplotypeFrequency†NSNPs*p value‡Power§
rs1051219rs1051233rs755437
*Haplotype analysis only given for the three SNPs showing association with asthma individually.
†Haplotypes with frequency <0.015 are not shown.
‡H0 =  no linkage and no association. Numbers in parentheses are p values corrected for linkage: H0 =  linkage and no association. Significance and power are calculated using PBAT.
§Conditional power estimated by PBAT.
¶Results from sample 1 are not given as none of the SNPs showed association with asthma.
Sample 2¶
H10.46102tcc0.096 (0.13)1 (1)
H20.2688tct 0.0068 (0.013) 1 (0.95)
H30.1977cgt0.83 (0.85)1 (1)
H40.04224ccc0.64 (0.67)0.14 (0.20)
H50.02613cgc 0.0047 (0.043) 1 (0.62)
Samples 1+2
H10.49130tcc0.20 (0.23)1 (1)
H20.26109tct 0.016 (0.026) 1 (1)
H30.20103cgt0.69 (0.72)0.79 (0.65)
H40.02625ccc0.54 (0.58)1 (0.89)
H50.01714cgc 0.0049 (0.044) 0.05 (0.20)