Haplotype | Frequency† | N | SNPs* | p value‡ | Power§ | ||
---|---|---|---|---|---|---|---|
rs1051219 | rs1051233 | rs755437 | |||||
*Haplotype analysis only given for the three SNPs showing association with asthma individually. | |||||||
†Haplotypes with frequency <0.015 are not shown. | |||||||
‡H0 = no linkage and no association. Numbers in parentheses are p values corrected for linkage: H0 = linkage and no association. Significance and power are calculated using PBAT. | |||||||
§Conditional power estimated by PBAT. | |||||||
¶Results from sample 1 are not given as none of the SNPs showed association with asthma. | |||||||
Sample 2¶ | |||||||
H1 | 0.46 | 102 | t | c | c | 0.096 (0.13) | 1 (1) |
H2 | 0.26 | 88 | t | c | t | 0.0068 (0.013) | 1 (0.95) |
H3 | 0.19 | 77 | c | g | t | 0.83 (0.85) | 1 (1) |
H4 | 0.042 | 24 | c | c | c | 0.64 (0.67) | 0.14 (0.20) |
H5 | 0.026 | 13 | c | g | c | 0.0047 (0.043) | 1 (0.62) |
Samples 1+2 | |||||||
H1 | 0.49 | 130 | t | c | c | 0.20 (0.23) | 1 (1) |
H2 | 0.26 | 109 | t | c | t | 0.016 (0.026) | 1 (1) |
H3 | 0.20 | 103 | c | g | t | 0.69 (0.72) | 0.79 (0.65) |
H4 | 0.026 | 25 | c | c | c | 0.54 (0.58) | 1 (0.89) |
H5 | 0.017 | 14 | c | g | c | 0.0049 (0.044) | 0.05 (0.20) |