Baseline characteristics of patients with neuromuscular weakness and kyphoscoliosis, and statistical difference between the two groups
| Characteristics | Neuromuscular weakness(n = 12) | Kyphoscoliosis(n = 8) | p value |
|---|---|---|---|
| BMI, body mass index; Paco2, arterial carbon dioxide tension; Pao2, arterial oxygen tension; Ptcco2, transcutaneous CO2 pressure; ESS, Epworth sleepiness score; PiMax, maximum inspiratory mouth pressure; Poes, oesophageal pressure; PeMax, maximum expiratory mouth pressure; Sniff Pdi, sniff transdiaphragmatic pressure; TwPdi, twitch transdiaphragmatic pressure; TLC, total lung capacity; FRC, functional residual capacity; RV, residual volume; CLung, lung compliance; CCW, chest wall compliance. | |||
| Anthropometric data | |||
| Sex (M:F) | 9:3 | 4:4 | |
| Age (years) | 64 (14) | 56 (14) | 0.23 |
| BMI (kg/m2) | 28 (6) | 21 (6) | 0.041 |
| Pao2 (kPa) | 8.3 (1.2) | 8.3 (1.4) | 0.76 |
| Paco2 (kPa) | 7.2 (1.9) | 7.2 (0.9) | 0.76 |
| Peak nocturnal Ptcco2 (kPa) | 9.1 (1.3) | 9.1 (1.7) | 0.58 |
| ESS (out of 24) | 10.0 (4.2) | 8.4 (5.2) | 0.41 |
| Muscle strength | |||
| PiMax (cm H2O) | 30 (1) | 41 (14) | 0.021 |
| Poes (cm H2O) | 41 (14) | 47 (10) | <0.001 |
| PeMax (cm H2O) | 67 (28) | 70 (30) | 0.19 |
| Sniff Pdi (cm H2O) | 33 (24) | 78 (43) | 0.005 |
| TwPdi (cm H2O) | 2.1 (3.0) | 10.8 (7.4) | 0.15 |
| Lung function | |||
| TLC (% predicted) | 62 (9) | 50 (7) | 0.09 |
| FRC (% predicted) | 73 (15) | 65 (14) | 0.19 |
| RV (% predicted) | 92 (28) | 87 (21) | 0.44 |
| Static compliance | |||
| CLung (ml/cm H2O) | 85 (18) | 71 (20) | 0.048 |
| CCW (ml/cm H2O) | 104 (29) | 63 (26) | 0.018 |