Table 1

Characteristics of study subjects

Patient no	FEV₁(% pred)	FEV₁/FVC(%)	PC₂₀ MCh(mg/ml)	RV(% pred)	TLC(% pred)	Feno(ppb)	8-isoprostane*(pg/ml)	δN₂(%N₂/l)	CV/VC(%)	CC/TLC(%)
FEV₁ % pred, forced expiratory volume in 1 second as percentage of predicted; PC₂₀MCh, provocative concentration of methacholine causing a 20% fall in FEV₁; RV, residual volume; TLC, total lung capacity; Feno, fractional exhaled nitric oxide; δN₂, slope of the nitrogen alveolar plateau (phase III); CV/VC, closing volume as percentage of vital capacity; CC/TLC closing capacity as percentage of total lung capacity.
*Note that the values result from correction for the concentration factor (threefold).
†Geometric mean (SD).
‡Median.
1	118	90.7	0.55	123	117	42.3	2.0	1.10	0.00	28.34
2	105	81.2	4.18	106	110	16.3	2.0	0.70	3.89	29.86
3	98	87.9	0.46	66	90	82.8	1.6	1.70	4.27	23.62
4	88	83.2	0.86	78	88	56.1	2.7	1.80	9.92	31.77
5	84	86.6	1.88	91	84	19.9	2.7	1.40	21.40	44.54
6	84	70.3	0.18	124	98	52.5	2.0	1.10	16.39	40.38
7	97	83.2	0.33	84	94	48.4	2.2	1.20	7.24	29.67
8	122	89.5	0.05	96	112	53.3	2.0	1.40	3.25	25.88
9	80	76.9	0.17	142	98	29.5	2.5	1.45	15.06	43.40
10	104	72	0.69	79	113	23.4	2.3	0.60	14.85	31.01
11	97	75.6	0.4	125	112	10.1	2.3	0.90	9.13	26.40
12	85	72.1	0.06	66	94	26.7	2.3	0.50	6.55	24.51
13	95	77.8	1.46	72	96	30.2	2.0	0.50	5.19	24.49
14	110	78.5	0.41	126	115	30.6	2.0	0.75	9.69	41.50
15	86	80.8	0.28	96	92	31.0	2.2	0.80	4.10	31.25
16	104	84.2	1.29	74	98	21.2	2.0	1.05	7.52	26.55
Mean (SD)	97.3 (12.6)	80.6 (6.3)	0.45† (3.3)	97 (24.6)	101 (10.7)	30.4‡	2.1‡	1.1 (0.4)	8.6 (5.7)	31.4 (7.1)