Table 2

 Clinical outcomes of participants in the Lung Health Study according to quintiles of baseline CRP levels

Quintile 1(n = 960)Quintile 2(n = 961)Quintile 3(n = 961)Quintile 4(n = 961)Quintile 5(n = 960)p for trend†
CHD, coronary heart disease; CVD, cardiovascular disease.
*Geometric mean value for each quintile of CRP.
†Linear trend from quintile 1 to quintile 5.
Variables presented as number of participants (% column totals) unless otherwise indicated.
Mean CRP (mg/l)*0.210.731.392.587.06
Total deaths47 (4.9)50 (5.2)61 (6.4)65 (6.8)106 (11.0)<0.001
CHD deaths7 (0.7)5 (0.5)8 (0.8)9 (0.9)22 (2.3)0.001
CVD deaths13 (1.4)7 (0.7)17 (1.8)17 (1.8)33 (3.4)<0.001
Fatal/non-fatal CHD68 (7.1)85 (8.8)86 (9.0)119 (12.4)145 (15.1)<0.001
Fatal/non-fatal CVD120 (12.5)133 (13.8)147 (15.3)187 (19.5)237 (24.7)<0.001
Cancer deaths21 (2.2)32 (3.3)29 (3.0)37 (3.9)50 (5.2)0.001
Lung cancer deaths13 (1.4)23 (2.4)15 (1.6)20 (2.1)28 (2.9)0.053
Respiratory deaths8 (0.8)3 (0.3)6 (0.6)3 (0.3)6 (0.6)0.578