Clinical outcomes of participants in the Lung Health Study according to quintiles of baseline CRP levels
| Quintile 1(n = 960) | Quintile 2(n = 961) | Quintile 3(n = 961) | Quintile 4(n = 961) | Quintile 5(n = 960) | p for trend† | |
|---|---|---|---|---|---|---|
| CHD, coronary heart disease; CVD, cardiovascular disease. | ||||||
| *Geometric mean value for each quintile of CRP. | ||||||
| †Linear trend from quintile 1 to quintile 5. | ||||||
| Variables presented as number of participants (% column totals) unless otherwise indicated. | ||||||
| Mean CRP (mg/l)* | 0.21 | 0.73 | 1.39 | 2.58 | 7.06 | |
| Total deaths | 47 (4.9) | 50 (5.2) | 61 (6.4) | 65 (6.8) | 106 (11.0) | <0.001 |
| CHD deaths | 7 (0.7) | 5 (0.5) | 8 (0.8) | 9 (0.9) | 22 (2.3) | 0.001 |
| CVD deaths | 13 (1.4) | 7 (0.7) | 17 (1.8) | 17 (1.8) | 33 (3.4) | <0.001 |
| Fatal/non-fatal CHD | 68 (7.1) | 85 (8.8) | 86 (9.0) | 119 (12.4) | 145 (15.1) | <0.001 |
| Fatal/non-fatal CVD | 120 (12.5) | 133 (13.8) | 147 (15.3) | 187 (19.5) | 237 (24.7) | <0.001 |
| Cancer deaths | 21 (2.2) | 32 (3.3) | 29 (3.0) | 37 (3.9) | 50 (5.2) | 0.001 |
| Lung cancer deaths | 13 (1.4) | 23 (2.4) | 15 (1.6) | 20 (2.1) | 28 (2.9) | 0.053 |
| Respiratory deaths | 8 (0.8) | 3 (0.3) | 6 (0.6) | 3 (0.3) | 6 (0.6) | 0.578 |