Incidence rates and adjusted hazard ratios (HRs) of CHD in relation to asthma variables: ARIC, 1987–2000
| Asthma definition | No of events | Incidence rate* | Model 1 HR† | 95% CI | Model 2 HR‡ | 95% CI |
|---|---|---|---|---|---|---|
| Maximum number of person-years was 154 315 and maximum number of events was 1250. Some subgroups have less because of missing data. | ||||||
| *Crude (per 1000 person-years). | ||||||
| †Model 1 adjusted for age, sex, and race/centre. | ||||||
| ‡Model 2 adjusted for age, sex, race/centre, HDL cholesterol, LDL cholesterol, systolic blood pressure, hypertension medication use, smoking status, pack years, W/H ratio, diabetes diagnosis, and sport score. | ||||||
| Never | 1185 | 8.12 | 1.0 | – | 1.0 | – |
| Ever | 64 | 7.81 | 0.95 | 0.74 to 1.23 | 0.87 | 0.66 to 1.14 |
| Former | 35 | 8.85 | 1.04 | 0.75 to 1.46 | 1.04 | 0.73 to 1.49 |
| Current | 28 | 6.81 | 0.86 | 0.59 to 1.26 | 0.69 | 0.46 to 1.05 |
| Asthma duration | ||||||
| Never | 1185 | 8.12 | 1.0 | – | 1.0 | – |
| Current or former | ||||||
| ⩽20 years | 44 | 8.74 | 1.06 | 0.78 to 1.44 | 1.03 | 0.75 to 1.42 |
| >20 years | 16 | 6.22 | 0.79 | 0.48 to 1.29 | 0.50 | 0.34 to 1.06 |
| Time dependent | ||||||
| No asthma | 1164 | 8.38 | 1.0 | – | 1.0 | – |
| Asthma | 85 | 5.51 | 0.93 | 0.74 to 1.15 | 0.88 | 0.69 to 1.11 |
| Wheeze attack | ||||||
| No wheeze attack with shortness of breath | 1124 | 8.09 | 1.0 | – | 1.0 | – |
| Wheeze attack with shortness of breath | 126 | 8.16 | 1.07 | 0.89 to 1.26 | 1.02 | 0.84 to 1.24 |