Table 1

Studies that assess HRQL or QOL in patients with IPF included in this review

Study no	Investigators	Study objectives	Measurement instruments used
SGRQ, St George’s Respiratory Questionnaire; SF-36, Medical Outcomes Study Short Form-36; WHOQOL-100, WHO Quality of Life 100 Item Instrument.
*Dutch version; †Portuguese version; ‡Japanese version.
1	De Vries et al¹⁹	(1) Identify life domains relevant to patients with IPF	SGRQ*
		(2) Determine whether the SGRQ or WHOQOL-100 was preferred for assessing these aspects	WHOQOL-100*

2	Martinez et al²¹	(1) Examine associations between HRQL and measures of dyspnoea and pulmonary function	SF-36†
		(2) Compare HRQL in patients with IPF and healthy people

3	De Vries et al²⁰	(1) Assess QOL in IPF patients	WHOQOL-100*
		(2) Identify clinical parameters related to QOL	WHOQOL-100*
		(3) Determine clinical predictors of QOL scores

4	Martinez et al²²	Examine association between HRQL and multiple dyspnoea scales	SF-36†

5	Nishiyama et al¹⁶	(1) Identify the association between clinical markers of disease severity and HRQL	SGRQ‡
		(2) Examine the relationship between HRQL and both dyspnoea and exercise capacity

6	Douglas et al²³	Clinical trial of colchicine versus prednisone	SF-36

7	Raghu et al²⁴	Clinical trial of interferon-γ versus placebo	SGRQ